Filippo Carlucci Selected Research

pegademase bovine (pegADA)

11/2017	Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients.
2/2012	Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.

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Filippo Carlucci Research Topics

Disease

10	Severe combined immunodeficiency due to adenosine deaminase deficiency 02/2024 - 05/2002
9	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 02/2024 - 06/2002
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 04/2024
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2024
1	Metabolic Diseases (Metabolic Disease) 01/2016
1	Reinfection 02/2012
1	Hypothyroidism 02/2012
1	Colorectal Neoplasms (Colorectal Cancer) 07/2010
1	Hypertension (High Blood Pressure) 01/2009
1	Infections 01/2009
1	Neutropenia 01/2009
1	Autoimmune Hepatitis 01/2009
1	Necrosis 01/2009
1	Methylmalonic acidemia 06/2007

Drug/Important Bio-Agent (IBA)

10	Adenosine DeaminaseIBA 02/2024 - 06/2002
5	purineIBA 02/2012 - 11/2006
3	Adenosine (Adenocard)FDA LinkGeneric 11/2017 - 04/2008
2	Busulfan (Busulfex)FDA Link 02/2024 - 01/2009
2	pegademase bovine (pegADA)FDA Link 11/2017 - 02/2012
2	EnzymesIBA 01/2009 - 05/2002
2	Proteins (Proteins, Gene)FDA Link 04/2008 - 06/2007
1	AutoantibodiesIBA 02/2012
1	fibrin fragment D (D-dimer)IBA 07/2010
1	Tumor Biomarkers (Tumor Markers)IBA 07/2010
1	Indicators and Reagents (Reagents)IBA 07/2010
1	OsteoprotegerinIBA 10/2009
1	CytokinesIBA 04/2008
1	Coenzymes (Enzyme Cofactors)IBA 06/2007
1	HomocysteineIBA 11/2003
1	Purine-Nucleoside PhosphorylaseIBA 11/2003
1	2'-deoxyadenosineIBA 11/2003
1	HydrolasesIBA 11/2003

Therapy/Procedure

2	Enzyme Replacement Therapy 11/2017 - 11/2006
1	Aftercare (After-Treatment) 04/2024
1	Stem Cell Transplantation 11/2017
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 02/2012
1	Central Venous Catheters 01/2009
1	Therapeutics 11/2003